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Fast-track hip and knee replacement
Grant application
Center Management

Fast-track hip and knee replacement
The concept is based on information, motivation and logistics, as well as the use of available evidence-based interventions within all sub-areas of treatment, care, rehabilitation, anesthesia pain management etc.

The main results show that hospitalization periods without the supply of resources can be reduced to approximately 1-2 days - while maintaining a very high patient satisfaction, and few complications.

In The Lundbeck Foundation Centre for Fast-track Hip and Knee Replacement- an interdisciplinary organization-, we conduct multimodal interventions to further optimize the outcome for knee and hip replacement patients. We focus especially on pain management, transfusion strategy, effect of physiotherapy, postoperative cognitive dysfunction, optimised thromboembolic prophylaxis, safety and morbidity monitoring and evaluation of hip dislocation and loosening of the prosthesis.

The outlined research will have far-reaching perspectives in other surgical populations.

They aim ultimately at a reduced need for hospitalization for 1-2 days, with concomitant increased security and fewer complications and rehabilitation needs.

Definition of fast-track
Fast-track is defined as a hospitalization, which provide the best possible evidence-based treatment pre-, intra- and postoperatively.


Viktoria Lindberg-Larsen, MD, will defend her PhD thesis on ” The effect of preoperative glucocorticoid on physiological responses to fast-track hip and knee arthroplasty” on January 25, 2018 at 14.00 at Bispebjerg Hospital, Auditorium L, Bispebjerg Bakke 23, 2400 København NV, DK. Everybody's welcome!
Troels Haxholdt Lunn, MD, PhD, will defend his doctoral thesis on ”Postoperative pain management in total hip and knee replacement” on February 2, 2018 at 14.00 at Medicinsk Museion, Bredgade 62, 1260 København K, DK. Everybody's welcome!

Latest publications
Preoperative methylprednisolone does not reduce loss of knee-extension strength after total knee arthroplasty. A randomized, double-blind, placebo-controlled trial of 61 patients
Lindberg-Larsen VO, Bandholm T, Zilmer CK, Bagger J, Hornsleth M, Kehlet H
Early patient-reported outcomes versus objective function after total hip- and knee arthroplasty: a prospective cohort study
Luna IE, Kehlet H, Peterson B, Wede HR, Hoevsgaard SJ, Aasvang EK
Delirium after fast-track hip and knee arthro-plasty - a cohort study of 6331 elderly patients
Petersen PB, J°rgensen CC, Kehlet H

Lundbeck Foundation Centre for Fast-track Hip and Knee Replacement..
Rigshospitalet, Section for Surgical Pathophysiology, Blegdamsvej 9, DK-2100 Copenhagen Ø Tel.: +45 3545 4074
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